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科研抗體

EGFRt單抗

EGFRt單抗

【名稱】anti-EGFRt antibody 【儲存條件】-20°C保存
【貨號】IAB001A 【有效期】半年
【包裝規格】100μg/管 【生產廠家】愛康得生物

產品介紹

人源EGFR蛋白是一種跨膜受體,它可作為酪氨酸激酶受體與同源配體結合,激活多種信號級并將胞外信號轉化為合適的細胞反應。其同源配體如表皮生長因子(EGF)和轉化生長因子α(TGFα)與細胞外結構域的結合導致EGFR二聚化,以及酪氨酸殘基在細胞質結構域中的自磷酸化。

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PD1單抗

PD1單抗

【名稱】anti-PD1 antibody 【儲存條件】-20°C保存
【貨號】IAB002A 【有效期】半年
【包裝規格】100μg/管 【生產廠家】愛康得生物

產品介紹

人源PD-1蛋白通常以單體形式存在,它含有免疫受體酪氨酸基抑制基序(ITIM),能夠在外周耐受和自身免疫性疾病中起重要作用。PD-1可作為細胞表面抑制受體參與T細胞免疫耐受性調節。與配體結合后,它能夠在抗原特異性水平上抑制T細胞效應。

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